Implanting Pacemaker Before Liver Transplant Does Not Lead to Better Outcomes, Study Reveals | oneAMYLOIDOSISvoice

Implanting Pacemaker Before Liver Transplant Does Not Lead to Better Outcomes, Study Reveals


Although most patients with familial amyloid polyneuropathy (FAP) who undergo liver transplant will require a pacemaker, implanting the device before the transplant is not beneficial, according to a new study. The research, “Pacemaker implantation in familial amyloid polyneuropathy: when and for whom?,” was published in the Journal of Interventional Cardiac Electrophysiology.
 
Cardiac manifestations in patients with FAP are due to dysautonomia — malfunction of the autonomic nervous system and deposits of the amyloid protein. Because these complications may persist after a liver transplant, which is the standard treatment for symptomatic FAP patients, implanting a pacemaker is important to prevent syncope (loss of consciousness usually due to insufficient blood flow to the brain) and sudden cardiac death.
 
Implanting Pacemaker Before Liver Transplant Does Not Lead To Better Outcomes, Study Reveals

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