Amyloidosis: What Every Physician Needs to Know | oneAMYLOIDOSISvoice
×
Or register here
Global Search

Trusted Resources: Education

Scientific literature and patient education texts

Back to Education / Reference Materials

Amyloidosis: What Every Physician Needs to Know

key information

source: Decision Support in Medicine

year: N/A

authors: David Seldin

summary/abstract:

Amyloidosis is a term for diseases caused by extracellular deposition of protein fibrils. The accepted nomenclature is “AX”, “A” for amyloidosis, and “X” indicating the precursor protein. If the precursor is an immunoglobulin light chain, the disease is termed AL, the most common of the systemic amyloidoses. If it is familial (AF), the precursor protein can be an inherited mutant serum protein such as transthyretin, abbreviated ATTR, or proteins such as lysozyme, fibrinogen, gelsolin, or apolipoproteins.
 
The old nomenclature of “primary” and “secondary” is no longer used, although AA amyloidosis, involving formation of fibrils from serum amyloid A (SAA) protein, is truly secondary to chronic inflammatory or infectious states, as SAA is an acute phase reactant.
 
read more

Related Content

To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences.
More information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close

Community Key Collaborator

Support for this landing page is provided by an independent education grant from

Translation of this platform made possible through an independent education grant from

© 2024 rareLife solutions Inc.

To improve your experience on this site, we use cookies. This includes cookies essential for the basic functioning of our website, cookies for analytics purposes, and cookies enabling us to personalize site content. By clicking on 'Accept' or any content on this site, you agree that cookies can be placed. You may adjust your browser's cookie settings to suit your preferences.
More information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close