source: Myeloma UK summary/abstract:
Diarrhoea is the passing of loose or watery stools more than three times a day. It can be acute (lasting only for a short time) or chronic (persisting for long periods, usually more than two weeks). If you have diarrhoea, it is important to deal with it straight away, as excessive loss of water through your stools can lead to dehydration, which can be serious. Any change in your regular bowel pattern which lasts longer than a few days should be reported to your doctor or nurse.
Diarrhoea can have a significant impact on your quality of life. It can make you anxious about leaving your home and stop you feeling able to perform your usual daily routine. Though you may feel uncomfortable or embarrassed talking about diarrhoea, try to remember that your doctor and nurse are used to talking about it and they are there to help prevent and manage any side-effects of AL amyloidosis and its treatment.