Emerging Treatments for Amyloidosis | oneAMYLOIDOSISvoice
Scientific Articles

Emerging Treatments for Amyloidosis

key information

source: Kidney International

year: 2015

authors: Sayed RH, Hawkins PN, Lachmann HJ


Amyloidosis results from protein misfolding, and ongoing amyloid deposition can ultimately lead to organ failure and death. Historically, this is a group of diseases with limited treatment options and frequently poor prognosis. However, there are now ‘targeted’ therapeutics emerging in the form of stabilizers of the precursor protein, inhibitors of fibrillogenesis, fibril disruptors, and blockers of protein translation, transcription, and immunotherapy. We review many of these approaches that are currently being assessed in clinical trials.

organization: UCL Medical School, UK

DOI: 10.1038/ki.2014.368

full text source


The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.