Systemic AA Amyloidosis Caused by Inflammatory Hepatocellular Adenoma | oneAMYLOIDOSISvoice
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Systemic AA Amyloidosis Caused by Inflammatory Hepatocellular Adenoma

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source: The New England Journal of Medicine

year: 2018

authors: Calderaro J, Letouzé E, Bayard Q, Boulai A, Renault V, Deleuze JF, Bestard O, Franco D, Zafrani ES, Nault JC, Moutschen M, Zucman-Rossi J

summary/abstract:

A woman presented with AA amyloidosis that was found to be caused by a genetic lesion in an inflammatory hepatocellular adenoma that led to overproduction of interleukin-6. Resection of the liver tumor led to improvement in the symptoms of amyloidosis.

organization: Henri Mondor University Hospital, France; INSERM Unité 1162, France; Centre National de Recherche en Génomique Humaine, France; Bellvitge University Hospital, Spain; Antoine Béclère University Hospital, France; Liege University Hospital, Belgium

DOI: 10.1056/NEJMc1805673

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