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Breast Amyloidosis: A Case Report and Literature Review

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source: Journal of the Belgian Society of Radiology

year: 2022

authors: Anne-Sofie De Crem, Koen Van de Vijver, Pieter De Visschere, Rudy Van den Broecke, Menekse Göker

summary/abstract:

Amyloidosis is an uncommon disorder characterized by extracellular accumulation of misfolded proteins in tissues. We report a unique case of localized breast amyloidosis in an asymptomatic 56-year-old woman with systemic lupus erythematosus, presented as suspicious microcalcifications without mass on mammography. Vacuum biopsy confirmed amyloidosis, producing the typical apple-green birefringence under polarized light after staining with Congo-red.

Further workup and follow-up to exclude development into systemic amyloidosis or hematologic malignancy is recommended. If negative, the prognosis is very good, thus no further treatment is needed. A brief review of the literature revealed more about the typical findings and recommended management.

organization: Ghent University Hospital, Belgium

DOI: 10.5334/jbsr.2988

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